FENG: About the project
Total project costs: 33 936 081,66 zł
Eligible costs: 27 956 095,00 zł
Funding: 23 483 119,80 zł
Project implementation time: 01.07.2025 – 30.06.2028
Project No.: FENG.02.04-IP.04-0005/24- 00
The main objective of the project is to develop the research potential of 7 laboratories forming part of the Center for the Development of Therapies for Civilization and Age-Related Diseases, by creating two highly advanced research modules: a molecular imaging module (with a new microdissection laboratory) and an advanced safety pharmacology module.
The project concerns the expansion of the existingCenter for the Development of Therapies for Civilization and Age-Related Diseases (CDT-CARD), the main component of which currently consists of 10 unique research laboratories on a national scale, focused on the practical use of results in the field of research on the pathogenesis of diseases of civilization and age-related diseases, identification of new therapeutic targets, creation of drug candidates and verification of new methods of therapy.
The funding obtained under the project will allow for the purchase of modern equipment, and consequently increase the research capabilities of CDT-CARD and its potential to create innovations. New research functionalities, expanding the current capabilities of CDT-CARD include: a laser microdissection laboratory (enabling the implementation of spatial omics techniques); a single-cell proteomics module (Single-Cell Proteomics (SCP) based on a new ultrasensitive mass spectrometer), a dynamic imaging module in increased resolution with validation of molecular targets at the RNA, DNA and protein levels with analysis of cell movements in microfluidic systems, as well as a module for comprehensive testing of drug interactions with key ion channels (QPatch Compact system) – they will create a key research platform, enabling the conduct of modern and fully comprehensive research on the development of new drugs.
What is extremely important, the equipment proposed for purchase will create the first platforms in Poland designed for such advanced imaging analyses, SCP analyses and electrophysiological studies. By enriching CDT-CARD with new research modules, further development and strengthening of research and innovation capabilities will take place, as well as the use of advanced technologies within this unique research center on a national scale. This will contribute to increasing the ability of the science sector to cooperate with economic entities, especially from the pharmaceutical and biotechnology sectors, because it provides for both the participation of enterprises in conducting research (as part of scientific and industrial consortia) and the possibility of making the infrastructure created available to enterprises on commercial terms, in conditions of equal and non-discriminatory access. The forecasted cooperation with the economy sector will translate into a greater number of implementations of R&D results, strengthening of National Smart Specializations, especially in the areas of medical and pharmaceutical sciences, as well as the introduction to the market of innovative and effective drugs and therapies, responding to the needs of an ageing society on a global scale.
The functionalities of the CDT-CARD expanded as a result of the project will increase the portfolio of research services, becoming an even more attractive platform for cooperation with external partners. Thanks to this, the Center will be able to better implement research cooperation with scientific units and the economic sector in R&D projects. Moreover, the additional functionality of CDT-CARD will strengthen its position on the research market in the field of early stage discovery and early preclinical development, both domestically and internationally. The purchased research equipment in the form of 14 pieces of advanced research devices will be integrated, and 7 central laboratories co-creating CDT-CARD, equipped with modern specialist equipment and access to the latest research techniques, including advanced -omic techniques (including a new laser microdissection laboratory), will be a unique unit on a national scale.
In addition, the Project includes training activities aimed at CDT-CARD research staff so that scientists are fully prepared not only to operate advanced research equipment, but above all to manage research infrastructure as effectively as possible in the context of planned cooperation with the economic sector and commercialization of research and development results, as well as obtaining a certificate according to the ISO/IEC 17025:2017 standard by the Small Molecule Analysis Laboratory, which is of significant importance from the point of view of competitiveness and ensuring the highest quality of research services provided.
More information about the project at this link: https://cdt-card.cm-uj.krakow.pl/
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