Scientific publications using the CDT-CARD research infrastructure
N-terphenylpicolinamide derivatives designed to target PD-L1 increase activation and proliferation of T cells, and their cytotoxic properties toward cancer cells
Factors Influencing the Dispersibility of Glycopyrronium Bromide and Indacaterol Maleate – Combined In Vitro and In Silico Study
Rational Design, Synthesis and Pharmacological Evaluation of Chalcones as Dual-Acting Compounds—Histamine H3 Receptor Ligands and MAO-B Inhibitors
Neuroprotection by post-stroke administration of the slow-releasing hydrogen sulfide (H2S) donor AP39: Long-Term functional, MRI, and molecular evidence in a rodent stroke model
N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d] imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer’s disease
Uncovering Urinary Proteome Differences in Very Preterm Infants with and without Preterm Brain Injury.
Comparative effectiveness of moderate treadmill training and venlafaxine treatment on long-lasting brain changes induced by prenatal dexamethasone exposure.
The mitochondria-targeted hydrogen sulfide donor AP39 reduces cortical stroke volume and improves motor function in a photothrombotic stroke model in mice in a sex-dependent manner
Optimization of Impedance-Based Real-Time Assay in xCELLigence RTCA SP16 Device for the Analysis of Fully Differentiated Caco-2 Cells
Photodegradation Assessment of Calcipotriol in the Presence of UV Absorbers by UHPLC/MSE
Preterm functional outcomes are reflected in early postnatal proteome changes
Restoration of biomechanical and biological conditions for the finger implant to properly assess the suitability of the implant
Discovery of new dual butyrylcholinesterase (BuChE) inhibitors and 5-HT7 receptor antagonists as compounds used to treat Alzheimer’s disease symptoms
Simultaneous Quantification of Bioactive Triterpene Saponins Calenduloside E and Chikusetsusaponin IVa in Different Plant Parts of Ten Amaranthaceae Species by UPLC-ESI-MS/MS Method
Biotransformation of oxybenzone and 3-(4-methylbenzylidene)camphor in Cunninghamella species: Potential for environmental clean-up of widely used sunscreen agents
Insight into the Structure of the Neutral Amino Acid Transporter B0AT2 Enabled the Discovery of Tiagabine as an Inhibitor
Quantitative proteomics in rat saliva stimulated with pilocarpine and isoprenaline
Preferential Synaptic Type of GABA‑A Receptor Ligands Enhancing Neuronal Survival and Facilitating Functional Recovery After Ischemic Stroke
Method Validation for the Determination of Ciprofloxacin in Lucilia sericata Larvae via Capillary Electrophoresis Combined With Mass Spectrometry
The Effect of Isometric Exercise Position on the Effectiveness of Isolated Work of the Thigh Flexor Muscles Based on the Results of the sEMG Study
Development of a Formulation and In Vitro Evaluation of a Pulmonary Drug Delivery System for a Novel Janus Kinase (JAK) Inhibitor, CPL409116
SerotoninAI software as a disruptive technology in Antidepressant Drug Discovery
Wystąpienie na AAPS Using AI/ML What is Lacking to Make AI/ML Really Successful in the Drug Discovery/Development Processes
EN_article “Integrated Profiling Identifies Long‑Term Molecular Consequences of Prenatal Dexamethasone Treatment in the Rat Brain—Potential Triggers of Depressive Phenotype and Cognitive Impairment” in Molecular Neurobiology
EN_article “Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by changing macrophage phenotypes and increasing UCP1 expression in vascular smooth muscle cells” in Biomedicine & Pharmacotherapy
EN_article “Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathways” in Pharmacological Research
EN_article “Alterations in plasma proteome during acute COVID-19 and recovery” in Molecular Medicine
EN_ article “Neuroprotective Effects of VGLUT1 Inhibition in HT22 Cells Overexpressing VGLUT1 Under Oxygen Glucose Deprivation Conditions” in NeuroMolecular Medicine
EN_article “Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes”
EN_article “Physiological healing of chronic gastric ulcer is not impaired by the hydrogen sulphide (H2S)-releasing derivative of acetylsalicylic acid (ATB-340): functional and proteomic approaches” in Inflammopharmacology
EN_article “The first report of the production of anatoxin-a by Bolivian terrestrial cyanobacteria”
EN_article “Chicago sky blue 6B exerts neuroprotective and anti-inflammatory effects on focal cerebral ischemia”
EN_article “The Hydrogen Sulfide Donor AP39 Reduces Glutamate-mediated Excitotoxicity in a Rat Model of Brain Ischemia”
EN_ article “Inhibition of Vesicular Glutamate Transporters (VGLUTs) with Chicago Sky Blue 6B Before Focal Cerebral Ischemia Offers Neuroprotection”
EN_article “Integrated QSAR Models for Prediction of Serotonergic Activity: Machine Learning Unveiling Activity and Selectivity Patterns of Molecular Descriptors” in Pharmaceutics 01.03.2024
EN_article “SerotoninAI: Serotonergic System Focused, Artificial Intelligence-Based Application for Drug Discovery” 30.01.2024
EN_article “In Vitro and In Vivo Testing of Stereolithography (SLA)-Manufactured Haemocompatible Photopolymers for Blood Pump” in Applied Sciences 31.12.2023
EN_article “Neuroprotective Activity of Enantiomers of Salsolinol and N‑Methyl‑(R)‑salsolinol: In Vitro and In Silico Studies” in ACS Omega 10.10.2023
EN_article “Activity of granulomatosis with polyangiitis and its correlation with mTOR phosphoproteomics in neutrophils” in Frontiers in Immunology 31.08.2023
EN_article “Application of automated machine learning in the identification of multi-target-directed ligands blocking PDE4B, PDE8A, and TRPA1 with potential use in the treatment of asthma and COPD” in Wiley Online Library 16.05.2023
EN_article “Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect” in Pharmaceuticals 30.04.2023
EN_ article “Artificial Intelligence-Based Quantitative Structure−Property Relationship Model for Predicting Human Intestinal Absorption of Compounds with Serotonergic Activity” in American Chemical Society, Chemistry for Life 21.04.2023
PL_Znaczenie reprezentacji molekularnej prezentacja prezentowana na konferencji TYGIEL XV w Lublinie_23-26 marca 2023
EN_article “Salsolinol Protects SH‑SY5Y Cells Against MPP+ Damage and Increases Enteric S100‑Immunoreactivity in Wistar Rats” in SpringerLink_30.11.2022
EN_Poster Hannover 2022
EN_Poster Strasbourg conference 27.06-01.07.2022
PL_Farmakologia przyszłości GL_Spotkanie naukowe w dniach 16-19 listopada 2021
EN_article “Do AutoML-Based QSAR Models Fulfill OECD Principles for Regulatory Assessment? A 5-HT1A Receptor Case” in Pharmaceutics_06.07.2021
EN_article “Curated Database and Preliminary AutoML QSAR Model for 5-HT1A Receptor” in Pharmaceutics_16.10.2021
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