Radioisotope and Functional Analysis Laboratory (RFAL)

The Radioisotope and Functional Analysis Laboratory (RFAL) is a vital part of the research infrastructure of the CDT-CARD Center, focusing on a comprehensive in vitro preclinical research platform aimed at developing new drug candidates and therapeutic strategies. 

RFAL offers a thorough and systematic evaluation of drug candidates’ interactions with biological targets, including complete pharmacological characterization of novel molecules. This is achieved using a wide range of techniques and research methods, such as radioisotopic studies, electrophysiological assays, cellular imaging techniques, label-free measurements of surface plasmon resonance and impedance, as well as microscale thermophoresis. 

In addition, RFAL’s activities encompass methods for identifying and characterizing new therapeutic targets (receptors, enzymes, transporters, and signaling molecules) by analyzing their roles and functions in in vitro and ex vivo models. 

The detailed research portfolio is available in the Research Capabilitiessection.